Best-rated hotels in Greenville for your unforgettable stay

Detailed descriptions, travelers’ reviews, and handpicked hotel collections will help you book your perfect accommodation.

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Choose from exclusive hotel collection

We offer thousands of Greenville hotels and accommodations from world's renowned hotel chains to unique gems of the region you won’t find anywhere else.

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Once you choose your best place to stay, take a minute to complete a quick reservation form and get an instant confirmation letter to your email address.

Benefit from flexible travel options

We provide the most flexible cancellation options, so you get your deposit back in case of a change of plans or other unforeseen circumstances.

Find a hotel

Hotels by class
4 stars 2
3 stars 1
2 stars 1
Unrated 42
Accommodation type
Holiday homes 31
Hotels 6
Apartments 4
Inns 2
Chalet 1
Bed & Breakfast 1
Aparthotel 1
Thematic Hotels
Vacation Rentals 30
Extended Stay 30
Pet-friendly hotels 23
Luxury accommodations 17
Private Villas 12
Cheap and budget hotels 11
Family Friendly hotels 10
Beach hotels 9
Beachfront hotels 9
Central hotels 4
Ski resorts 1
Luxury hotels 1
Jacuzzi 1
All Greenville hotels

Hotels by location

Nearby
City Center Greenville 15
Big Squaw Mountain Greenville 26
Moosehead Marine Museum 25
Landmarks
Museums
Popular attractions
Maine >
Greenville

Welcome to Greenville

Greenville, a charming city nestled in the heart of South Carolina, offers a bucketful of attractions for visitors to explore. Immerse yourself in the vibrant arts scene as you stroll through the picturesque downtown, filled with art galleries, theaters, and music venues. Indulge your taste buds with unique culinary experiences, from farm-to-table restaurants to trendy food trucks. Discover the great outdoors by hiking the scenic trails of Falls Park or taking a leisurely bike ride along the Swamp Rabbit Trail. Experience the hospitality of Greenville firsthand and create lasting memories. Plan your visit now and let Greenville enchant you.

What our users say about Greenville hotels

Holiday Inn Bar Harbor Regency Hotel By Ihg
9.8

Exceptional

us Daniel 18 September 2022
The breakfast options here are decent. I would definitely consider staying here again because it had everything we were looking for. 🌟
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Portland Harbor Hotel
9.8

Exceptional

us Clarence 02 March 2023
Hospitable hotel in a fantastic location close to the harbor and many great restaurants and bars. the hotel is in a magnificent position to everything in the old port. - Nearby the Royale Lunch Bar is a great place to chill out.
Had a good stay with no complaints.
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Anchorage Motel
9.6

Good

us Phil 13 March 2021
The hotel is very clean. It was next door to Bar Harbor city center...
None.
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Lodge At Kennebunk
9.4

Excellent

us John 10 February 2023
The room was kept very clean and had a table for eating or writing. Very comfortable beds. - There was a microwave oven and a fridge. - the setting was unbeatable, close to Kennebunk and Kennebunkport, beaches, and restaurants.
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Elmwood Resort Hotel
9.2

Excellent

us Dan 06 October 2022
I had a great stay here and I definitely plan to come back. The weather was fantastic and made my winter getaway even more enjoyable. The hotel is super close to Kennebunkport, which was really convenient for exploring the area.
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Aspinquid Resort
9.8

Exceptional

us Don 14 January 2023
I got guest room for 1 night, appreciated it. Really enjoyed a walk-in shower in my private bathroom. The location was easy for walking around Abacus Art Gallery. Besides, it was so close to the beach as well as restaurants.
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The Seaside Inn
7.2

Good

us Jerry 07 November 2020
This place is perfect for a wedding, with a tasty breakfast and great value for money, plus the beautiful beach is just a short distance away, and we absolutely enjoyed our stay here and would love to return.
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Ac Hotel Portland Downtown-Waterfront, Me
7.6

Good

us George 15 May 2021
It's convenient base for sightseeing and exploring Portland.
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Bluenose Inn - Bar Harbor Collection
9.8

Exceptional

us John 06 September 2020
Hotel is an ideal place for a weekend in Bar Harbor. We truly enjoyed comfortable beds in our room.
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Yankee Clipper Motel
7.0

Good

us Thomas 19 August 2020
We think it's a fine base for staying in Belfast. We greatly enjoyed a heating system, a writing desk and an ironing set.
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Save time on your trip arrangements by booking one of our hand-picked hotels

Best 4-star hotels
Exclusive 3-star hotels
Quality 2-star hotels
Experience the best value for your money by checking out our selection of 4-star Greenville hotels.
The Lodge At Moosehead Lake

368 Lily Bay Road, Greenville, United States

Good
5 reviews

679 US$

min. price/night

Greenville Inn At Moosehead Lake

40 Norris Street, Greenville, United States

Enjoy truly authentic experiences without compromising comfort and convenience.
Leisure Life Hotel

33 Leisure Life Road, Greenville, United States

Good
134 reviews

140 US$

min. price/night

Discover the hidden gems of Greenville by booking one of its budget-friendly hotels.
Kineo View Lodge

50 Overlook Drive, Greenville, United States

124 US$

min. price/night

Travelers’ choice

Check out the most booked accommodations to find reliable places that our users have tried and tested.
Camp Foxtrot Hotel

Greenville, United States

Excellent
9 reviews

156 US$

min. price/night

Upscale Moosehead Lake Suite Downtown Greenville

9 Pleasant St, Greenville, United States

Excellent
7 reviews

324 US$

min. price/night

All-Season Sanctuary: Steps To Moosehead Lake

18 S Birch St, Greenville, United States

Excellent
4 reviews

212 US$

min. price/night

Secluded Greenville Cabin: Walk To Moosehead Lake!

127 Ridge Pkwy, Greenville, United States

Excellent
4 reviews

276 US$

min. price/night

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